Rubella Immune Status of Pregnant & Non-pregnant women in Indian Population
نویسندگان
چکیده
Objective: This study was undertaken to determine in a cross-sectional survey whether rubella virus circulation in the Indian population induces detectable immunoglobulin G (IgG) antibodies with a protective level, in a random group of pregnant & nonpregnant women. Methods: Rubella-IgG antibody status was assessed in 1182 Indian women comprising of 617 pregnant women, 497 nonpregnant women of childbearing age group and 68 women who suffered from miscarriage. Results: Rubella IgG was detected in 91.73% of pregnant women, 88.93% of non-pregnant women of childbearing age and 92.65% of women who had miscarriage. Rubella IgG antibody titers amongst the Indian women studied ranged between 15-272 IU/ml. Conclusion: Majority of the Indian women appeared to possess protective level of Rubella IgG antibodies. However there is a significant group that does not posses the immunity. Screening to pick up such women is necessary so that rubella vaccine can be offered to such women for the protection of offspring's born in subsequent pregnancy.
منابع مشابه
An Investigation on Antirubella Immunoglobulin Titeres and the Level of Protectivity Among 5 Major Highly Populated Cities of Gilan Province
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Objective: Rubella is a viral disease with minor morbidity, unless it is contracted by a pregnant woman in early pregnancy that leads to congenitalRubella syndromes. Rubella occurrence during the first trimester leads to fetal death or severe congenital defects.Present study was conducted to survey the protection level against Rubella in the pregnant women of Gilan in IRAN,to be used for the va...
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